The Obesity and Disease Development Sweden (ODDS) study

In the study involving over 600,000 people, researchers at Lund University in Sweden have investigated how changes in weight between the ages of 17 and 60 are linked to the risk of dying from various diseases. The results show a clear pattern: weight gain early in adulthood has the greatest impact.

Lund university press release:

Early weight gain can have lifelong consequences | Lund University

Tidiga kilon kan få livslånga konsekvenser | Lunds universitet

Forskare bakom stor studie: Vid denna ålder bör du vara extra uppmärksam på din vikt i samband med för tidig död | illvet.se

Early weight gain is linked to lifelong health consequences | ScienceDaily

Weight gain in certain decade of life may be more dangerous, study suggests – Local News

Weight gain in your 20s may raise your risk of early death – Earth.com

Weight Gain in Early Adulthood Linked to Higher Premature Death Risk

Our study, titled “Weight trajectories and obesity onset between 17 and 60 years of age, and cause-specific mortality: the Obesity and Disease Development Sweden (ODDS) pooled cohort study”, has been published in eClinicalMedicine.

The findings suggest that weight gain across adulthood, particularly at younger ages, and early obesity onset are associated with higher mortality from many non-communicable diseases. Weight gain at younger ages is generally associated with higher risk than weight gain later in life, except for cancer mortality in women, where weight gain at any age appears to be associated with broadly similar risk.

Our study, Weight trajectories throughout adulthood and prostate cancer incidence, aggressiveness, and death in 258,494 men, was published in the Journal of the National Cancer Institute. The study suggests that steeper weight gain between ages 17 and 60 is associated with a higher risk of death from prostate cancer, with a stronger association for weight gain in late middle age (45–60 years). Associations with prostate cancer incidence appear to be strongly influenced by PSA testing uptake, which likely differs between men with high and low weight gain, making the interpretation of incidence findings more challenging.

Read more https://academic.oup.com/jnci/advance-article/doi/10.1093/jnci/djag014/8441228